Nattapong Jaimchariyatam, Carlos L. Rodriguez, Kumar Budur
Objectives:Obstructive sleep apnea (OSA) is associated with significant cardiovascular (CV) morbidity. Continuous positive airway pressure (CPAP) is the standard treatment for moderate to severe OSA, resulting in a reduction in CV morbidity. No studies have compared CV outcomes between CPAP and no CPAP in mild OSA (5PAHI < 15).
Busarakum Teerapraipruk&Naricha Chirakalwasan& Rosalind Simon&Prakobkiat Hirunwiwatkul& Nattapong Jaimchariyatam&Tayard Desudchit& Natamon Charakorn&Chaisiri Wanlapakorn
Introduction In Asian population, facial structure may contribute to the primary pathophysiology of obstructive sleep apnea (OSA). We hypothesized that sleep position may have more effect on OSA in Asians compared to the Western population. If this hypothesis is accurate, positional therapy will have a major impact on treatment of OSA among Asians. Patients/methodsWe reviewed 263 polysomnographic studies from our laboratory from January 1, 2010 to June 30, 2010. Criteria for positional and non-positional OSAwere (1) supine respiratory disturbance index (RDI)/non-supine RDI≥2 and total RDI ≥5 and (2) supine RDI/non-supine RDI <2 and total RDI ≥5, respectively. We aimed to determine the difference in baseline characteristics, polysomnographic findings, and predictors for positional OSA.
by NATTAPONG JAIMCHARIYATAM, MD, MSc, FCCP; CARLOS L. RODRIGUEZ, MD; and KUMAR BUDUR, MD, MS
Major depressive disorder is associated with sleep disturbances. An electroencephalographic pattern of alpha wave intrusion in delta wave sleep (alpha-delta sleep) is observed in some subjects with major depressive disorder. The treatmentresistant symptoms in major depressive disorder, nonrestorative sleep and fatigue, are associated with alpha-delta sleep. The objective of this study is to identify the prevalence and clinical correlates of alpha-delta sleep in major depressive disorder.